{"id":4865,"date":"2024-06-16T12:35:48","date_gmt":"2024-06-16T03:35:48","guid":{"rendered":"https:\/\/pro-clinic.jp\/?p=4865"},"modified":"2024-06-23T16:19:37","modified_gmt":"2024-06-23T07:19:37","slug":"ed20240616","status":"publish","type":"post","link":"https:\/\/xoway2.heteml.net\/pro-clinic\/ikemarapedia\/ed20240616\/","title":{"rendered":"ED\u85ac (\u52c3\u8d77\u4e0d\u5168\u6cbb\u7642\u85ac) \u306b\u3064\u3044\u3066"},"content":{"rendered":"\t\t
\n\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

<\/p>\n

\n\n<\/p>\n

\u7686\u69d8\u3053\u3093\u306b\u3061\u306f\uff01<\/p>\n

\n\n<\/p>\n

\u672c\u65e5\u306f\u4ee5\u524d\u306b\u5c11\u3057\u3054\u7d39\u4ecb\u3057\u305f<\/a> ED \u85ac\u306b\u3064\u3044\u3066\u304a\u8a71\u3055\u305b\u3066\u3044\u305f\u3060\u304f\u7b2c 1 \u5f3e\u3067\u3059\ud83d\udc8a<\/p>\n

\n\n<\/p>\n

\u7686\u69d8\u3001\u6700\u8fd1\u306e\u52c3\u3061\u5177\u5408\u3044\u304b\u304c\u3067\u3059\u304b\uff1f
\u306a\u3093\u304b\u6700\u8fd1\u52c3\u3061\u5177\u5408\u304c\u3088\u304f\u306a\u3044\u306a\uff5e\u30fb\u30fb\u30fb\u6700\u8fd1\u3059\u3050\u840e\u3048\u3061\u3083\u3046\u30fb\u30fb\u30fb
\u306a\u3093\u3066\u65b9\u591a\u3044\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

\n\n<\/p>\n

\u305d\u3093\u306a ED \u3092\u6539\u5584\u3067\u304d\u308b\u300c\u52c3\u8d77\u4e0d\u5168\u6cbb\u7642\u85ac\u300d\u3044\u308f\u3086\u308b\u300cED \u85ac\u300d\u3068\u3044\u3046\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\n\n<\/p>\n

\u4eca\u56de\u306f\u52c3\u8d77\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3084ED \u85ac\u3092\u4f7f\u7528\u3067\u304d\u306a\u3044\u4eba\u30fb\u76f8\u8ac7\u304c\u5fc5\u8981\u306a\u4eba\u3001ED \u85ac\u306e\u5165\u624b\u65b9\u6cd5\u306b\u3064\u3044\u3066\u304a\u8a71\u3057\u307e\u3059\u306d\uff01<\/p>\n

\n

\n\n<\/p>\n

\u52c3\u8d77\u306e\u30e1\u30ab\u30cb\u30ba\u30e0<\/strong><\/h3>\n

\u4eba\u9593\u306e\u8eab\u4f53\u306f\u6027\u7684\u523a\u6fc0\u3092\u611f\u3058\u308b\u3068<\/strong>\u3001\u8133\u306e\u4e2d\u67a2\u795e\u7d4c\u304c\u8208\u596e\u3057\u3001\u8eab\u4f53\u306e\u4e2d\u306e\u300c<\/strong><\/span>\u74b0\u72b6\u30b0\u30a2\u30ce\u30b7\u30f3\u4e00\u30ea\u30f3\u9178<\/strong> (cGMP)\u300d\u304c\u5408\u6210\u3055\u308c<\/strong>\u3001\u9670\u830e\u6d77\u7dbf\u4f53\u306b\u3042\u308b\u5e73\u6ed1\u7b4b\u304c\u7de9\u3080\u4e8b\u306b\u3088\u308a\u3001\u901a\u5e38\u3088\u308a\u3082\u591a\u304f\u306e\u8840\u6db2\u304c\u30da\u30cb\u30b9\u306b\u6d41\u5165\u3057\u3066\u52c3\u8d77\u3057\u307e\u3059<\/strong>\u3002<\/span><\/p>\n

\u305d\u306e\u307e\u307e\u52c3\u8d77\u3057\u305f\u72b6\u614b\u304c\u7d9a\u304f\u3068\u56f0\u3063\u3061\u3083\u3044\u307e\u3059\u3088\u306d\uff1f<\/span><\/p>\n

\u305d\u3046\u306a\u3089\u306a\u3044\u69d8\u306b\u3001\u4eba\u9593\u306e\u8eab\u4f53\u306b\u306f\u52c3\u8d77\u3092\u6291\u3048\u308b 5 \u578b<\/strong><\/span>\u30db\u30b9\u30db\u30b8\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc<\/strong>\u00a0(PDE-5)<\/strong> \u306e\u9175\u7d20\u6d3b\u6027\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306f\u524d\u8ff0\u3057\u305f\u3001\u52c3\u8d77\u3092\u4fc3\u3059\u3010cGMP\u3011\u3092\u5206\u89e3\u3059\u308b\u4f5c\u7528\u304c\u3042\u308b\u70ba\u3001\u8208\u596e\u304c\u843d\u3061\u7740\u304f\u3068\u52c3\u8d77\u304c\u53ce\u307e\u308b<\/strong>\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n

\u3061\u306a\u307f\u306b ED \u306f\u3001\u6027\u884c\u70ba\u6642\u306b\u3010PDE-5\u3011\u304c\u512a\u52e2\u306a\u5834\u5408\u306b\u8d77\u3053\u308a\u307e\u3059\u306e\u3067\u3001
ED\u85ac\u3067\u3010PDE-5\u3011\u3092\u963b\u5bb3\u3057\u3066\u3001\u52c3\u8d77\u306e\u6301\u7d9a\u3092\u4fc3\u9032\u3055\u305b\u307e\u3059\uff01

\u533b\u5e2b\u89e3\u8aac\u30da\u30fc\u30b8\u306f\u3053\u3061\u3089 \u2192 \u300c\u52c3\u8d77\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3068 ED \u85ac\u306e\u52b9\u679c \u300d<\/a><\/strong><\/span><\/p>\n

\n

ED \u85ac\u3092\u4f7f\u7528\u3067\u304d\u306a\u3044\u65b9\u30fb\u76f8\u8ac7\u304c\u5fc5\u8981\u306a\u65b9<\/strong><\/h3>\n

\u30fb\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u30af\u30a8\u30f3\u9178\u5869\u3001\u5869\u9178\u30d0\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u6c34\u548c\u7269\u3001
\u3000\u30bf\u30c0\u30e9\u30d5\u30a3\u30eb\u306e\u6210\u5206\u306b\u5bfe\u3057\u3066\u904e\u654f\u75c7\u306e\u3042\u308b\u65b9\u3084\u65e2\u5f80\u6b74\u306e\u3042\u308b\u65b9
<\/span>\u30fb\u5fc3\u8840\u7ba1\u7cfb\u969c\u5bb3\u3092\u6709\u3059\u308b\u306a\u3069\u6027\u884c\u70ba\u304c\u56f0\u96e3\u3068\u8003\u3048\u3089\u308c\u308b\u65b9
<\/span>\u30fb\u91cd\u5ea6\u809d\u6a5f\u80fd\u969c\u5bb3\u3068\u8a3a\u65ad\u3055\u308c\u3066\u3044\u308b\u65b9
<\/span>\u30fb\u5148\u5929\u6027QT\u5ef6\u9577\u75c7\u5019\u7fa4\u306e\u65b9
<\/span>\u30fb\u4f4e\u8840\u5727\u306e\u65b9
<\/span>\u30fb\u672a\u6cbb\u7642\u307e\u305f\u306f\u7ba1\u7406\u306e\u3055\u308c\u3066\u3044\u306a\u3044\u9ad8\u8840\u5727\u306e\u65b9
<\/span>\u30fb\u7db2\u819c\u8272\u7d20\u5909\u6027\u75c7\u306e\u65b9
<\/span>\u30fb\u8133\u6897\u585e\u3001\u8133\u51fa\u8840\u3001\u5fc3\u7b4b\u6897\u585e\u306e\u65e2\u5f80\u6b74\u304c 6 \u304b\u6708\u4ee5\u5185\u306b\u3042\u308b\u65b9
<\/span>\u30fb\u30a2\u30df\u30aa\u30c0\u30ed\u30f3\u5869\u9178\u5869 (\u7d4c\u53e3\u5264) \u3092\u6295\u4e0e\u4e2d\u306e\u65b9
<\/span>\u30fb\u30af\u30e9\u30b9IA (\u30ad\u30cb\u30b8\u30f3\u3001\u30b8\u30bd\u30d4\u30e9\u30df\u30c9\u7d4c\u53e3\u5264\u3001\u30d7\u30ed\u30ab\u30a4\u30f3\u30a2\u30df\u30c9\u3001\u30b7\u30d9\u30f3\u30be\u30ea\u30f3\u3001\u30d4\u30eb\u30e1\u30ce\u30fc\u30eb) \u307e\u305f\u306f\u3001
\u3000\u30af\u30e9\u30b9\u2162 (\u30bd\u30bf\u30ed\u30fc\u30eb\u3001\u30a2\u30df\u30aa\u30c0\u30ed\u30f3\u7d4c\u53e3\u5264) \u306e\u6297\u4e0d\u6574\u8108\u85ac\u3092\u6295\u4e0e\u4e2d\u306e\u65b9
<\/span>\u30fb\u30ea\u30aa\u30b7\u30b0\u30a2\u30c8\u3001CYP3A4\u3092\u963b\u5bb3\u3059\u308b\u85ac\u5264 (\u30ea\u30ca\u30eb\u30d3\u30f3\u3001\u30db\u30b9\u30a2\u30f3\u30d7\u30ec\u30ca\u30d3\u30eb\u3001\u30ed\u30d4\u30ca\u30d3\u30eb\u3001\u30c0\u30eb\u30ca\u30d3\u30eb\u3092\u542b\u6709\u3059\u308b\u88fd\u5264\u3001\u30a4\u30c8\u30e9\u30b3\u30ca\u30be\u30fc\u30eb\u3001\u30b1\u30c8\u30b3\u30ca\u30be\u30fc\u30eb (\u5916\u7528\u5264\u3092\u9664\u304f)\u3001\u30b3\u30d3\u30b7\u30b9\u30bf\u30c3\u30c8\u3092\u542b\u6709\u3059\u308b\u88fd\u5264) \u3092\u6295\u4e0e\u4e2d\u306e\u65b9
<\/span>\u30fb\u785d\u9178\u5264\u307e\u305f\u306f\u4e00\u9178\u5316\u7a92\u7d20 (No) \u4f9b\u4e0e\u5264 (\u30cb\u30c8\u30ed\u30b0\u30ea\u30bb\u30ea\u30f3\u3001\u785d\u9178\u30a4\u30bd\u30bd\u30d3\u30eb\u30c9\u3001\u4e9c\u785d\u9178\u30a2\u30df\u30eb\u3001\u30cb\u30b3\u30e9\u30f3\u30b8\u30eb\u7b49) \u3092\u6295\u4e0e\u4e2d\u306e\u65b9
<\/span>\u30fb\u53ef\u6eb6\u6027\u30b0\u30a2\u30cb\u30eb\u9178\u30b7\u30af\u30e9\u30fc\u30bc (sGC) \u523a\u6fc0\u5264 (\u30ea\u30aa\u30b7\u30b0\u30a2\u30c8) \u3092\u6295\u4e0e\u4e2d\u306e\u65b9<\/span><\/p>\n

\u4e0a\u8a18\u306b\u5f53\u3066\u306f\u307e\u308b\u65b9\u306f\u3001ED \u85ac\u3092\u5185\u670d\u3044\u305f\u3060\u3051\u307e\u305b\u3093\u3002
\u591a\u3059\u304e\u3066\u3088\u304f\u5206\u304b\u3093\u306a\u3044\u3088\uff01\u3063\u3066\u65b9\u3001\u304a\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\uff01<\/strong><\/span><\/p>\n

\n

ED \u85ac\u306e\u5165\u624b\u65b9\u6cd5<\/strong><\/h3>\n

\u30fb\u30d0\u30a4\u30a2\u30b0\u30e9\u30fb\u30d0\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u30fb\u30bf\u30c0\u30e9\u30d5\u30a3\u30eb\u306e\u52c3\u8d77\u4e0d\u5168\u6cbb\u7642\u85ac\u306f\u3001\u533b\u5e2b\u306e\u8a3a\u5bdf\u3068\u51e6\u65b9\u304c\u5fc5\u8981\u3067\u85ac\u3067\u3059\u3002<\/strong>
<\/span>\u30fb\u500b\u4eba\u8f38\u5165\u306e\u901a\u8ca9\u30b5\u30a4\u30c8\u306a\u3069\u3067\u306f\u3001<\/strong>\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306e\u51e6\u65b9\u3088\u308a\u3082\u5b89\u4fa1\u306b\u8cfc\u5165\u3067\u304d\u3066\u3057\u307e\u3046\u306e\u3067\u6a21\u9020\u54c1\u3084\u3001
\u3000\u5b89\u5168\u6027\u304c\u4fdd\u305f\u308c\u3066\u3044\u306a\u3044\u54c1\u8cea\u306e\u85ac<\/strong>\u304c\u5c4a\u3044\u3066\u3057\u307e\u3044\u3001\u601d\u308f\u306c\u5065\u5eb7\u88ab\u5bb3\u3092\u8d77\u3053\u3057\u304b\u306d\u307e\u305b\u3093\u3002
<\/span>\u30fb\u6709\u52b9\u6210\u5206\u306e\u542b\u6709\u91cf\u304c\u591a\u3051\u308c\u3070\u3088\u308a\u52b9\u679c\u304c\u3042\u308b\u306e\u3067\u306f\u306a\u3044\u304b\uff1f\u3068\u601d\u308f\u308c\u307e\u3059\u304c\u3001
\u3000\u57fa\u672c\u7684\u306b 100\u338e \u306a\u3069\u306e\u9ad8\u3044\u542b\u6709\u91cf\u306f\u65e5\u672c\u306b\u6d41\u901a\u3057\u3066\u304a\u308a\u307e\u305b\u3093\u306e\u3067\u3001\u7d76\u5bfe\u306b\u8cfc\u5165\u3057\u306a\u3044\u3088\u3046\u306b\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/strong><\/span><\/p>\n

\u25bc \u65e5\u672c\u56fd\u5185\u3067\u8cfc\u5165\u3057\u305f\u533b\u85ac\u54c1\u3084\u51e6\u65b9\u3055\u308c\u305f\u533b\u85ac\u54c1\u306b\u5bfe\u3057\u3066\u306f\u3001\u526f\u4f5c\u7528\u304c\u751f\u3058\u3066\u3082\u3010\u533b\u85ac\u54c1\u526f\u4f5c\u7528\u88ab\u5bb3\u6551\u6e08\u5236\u5ea6\u3011<\/strong>\u306e\u5229\u7528\u304c\u51fa\u6765\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002
<\/span>\u25bc \u3053\u308c\u3089\u306f\u3001\u533b\u85ac\u54c1\u306b\u3088\u308b\u526f\u4f5c\u7528\u3067\u3001\u6cbb\u7642\u8cbb\u306a\u3069\u306b\u304b\u304b\u3063\u305f\u5834\u5408\u306b\u4fdd\u8a3c\u3092\u53d7\u3051\u3089\u308c\u308b\u5236\u5ea6\u306b\u306a\u308a\u307e\u3059\u3002
<\/span>\u25bc\u3010\u672a\u627f\u8a8d\u3011\u306e\u6d77\u5916\u88fd\u533b\u85ac\u54c1\u3092\u3001\u500b\u4eba\u7684\u306b\u8f38\u5165\u30b5\u30a4\u30c8\u306a\u3069\u3067\u8cfc\u5165\u3057\u305f\u5834\u5408\u306f\u3001\u526f\u4f5c\u7528\u304c\u751f\u3058\u3066\u3082\u3053\u306e\u5236\u5ea6\u306f\u9069\u7528\u3055\u308c\u307e\u305b\u3093\u3002<\/strong><\/span><\/span><\/p>\n

\u203b \u5fc5\u305a\u3001\u5b89\u5168\u30fb\u5b89\u5fc3\u306b\u6cbb\u7642\u3059\u308b\u4e8b\u3092\u7b2c\u4e00\u306b\u5fc3\u304c\u3051\u3066\u304f\u3060\u3055\u3044 \u203b<\/strong><\/h3>\n

\n\n<\/p>\n

\n\n<\/p>\n


\u3044\u304b\u304c\u3067\u3057\u305f\u304b\uff1f<\/p>\n

\n\n<\/p>\n

\u4eca\u56de\u306f\u52c3\u8d77\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3084ED \u85ac\u3092\u4f7f\u7528\u3067\u304d\u306a\u3044\u4eba\u30fb\u76f8\u8ac7\u304c\u5fc5\u8981\u306a\u4eba\u3001ED \u85ac\u306e\u5165\u624b\u65b9\u6cd5\u3064\u3044\u3066
\u304a\u8a71\u3055\u305b\u3066\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3002
\u6b21\u56de\u306fED\u85ac\u306e\u7a2e\u985e\u306b\u3064\u3044\u3066<\/strong>\u3054\u7d39\u4ecb\u3057\u307e\u3059\u306e\u3067\u3001\u6c17\u306b\u306a\u308b\u65b9\u306f\u30c1\u30a7\u30c3\u30af\u3057\u3066\u307f\u3066\u304f\u3060\u3055\u3044\uff01<\/p>\n

\n\n<\/p>\n

\n\n<\/p>\n

\u5f53\u9662\u3067\u306f\u3001\u60a3\u8005\u69d8\u4e00\u4eba\u3072\u3068\u308a\u306e\u500b\u5225\u306e\u30cb\u30fc\u30ba\u306b\u5fdc\u3048\u308b\u30aa\u30fc\u30c0\u30fc\u30e1\u30a4\u30c9\u6cbb\u7642\u3092\u5fc3\u639b\u3051\u3066\u304a\u308a\u307e\u3059\u3002
\u4e01\u5be7\u306a\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3068\u78ba\u304b\u306a\u6280\u8853\u3067\u3001\u7406\u60f3\u306e\u4ed5\u4e0a\u304c\u308a\u3092\u76ee\u6307\u3057\u307e\u3059\u3002
\u3054\u81ea\u8eab\u306e\u7f8e\u3092\u8ffd\u6c42\u3055\u308c\u305f\u3044\u65b9\u306f\u3001\u305c\u3072\u5f53\u9662\u307e\u3067\u304a\u554f\u3044\u5408\u308f\u305b\u304f\u3060\u3055\u3044<\/p>\n

\n\n<\/p>\n

<\/p>\n

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\u00a0<\/div>\n

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